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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies as well as in peripheral

SKU: 41156754948

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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies as well as in peripheralThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

as well as in peripheral sites such as the small intestine and heart

Mutations in GDI1 have been linked to X-linked nonspecific mental retardation

It also stimulates prostacyclin production and cell adhesion

This protein interacts with polycystin 1

Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies as well as in peripheralThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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