Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays The gene mutation results in

The gene mutation results in primary NAA deficiency (hypoacetylaspartia)

Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described

This gene encodes a component of the Mediator complex

Y genotype

Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays The gene mutation results inRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine