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Rat Glutamate[NMDA] Receptor Subunit Epsilon-2, GRIN2B ELISA Kit, 96T Antibodies Cooperates with TLR1 or TLR6

SKU: 41425333202

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PLN185.49 PLN215.49

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Rat Glutamate[NMDA] Receptor Subunit Epsilon-2, GRIN2B ELISA Kit, 96T Antibodies Cooperates with TLR1 or TLR6Component of NMDA receptor complexes that function as heterotetrameric, ligand gated ion Channels with high calcium permeability and voltage dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate Channel inhibition by Mg(2+) (PubMed: 1350383, PubMed: 19910922, PubMed: 21677647, PubMed: 24876489,

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Description

Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852

At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene

Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis

This protein is a ligand for TNFRSF17/BCMA

Rat Glutamate[NMDA] Receptor Subunit Epsilon-2, GRIN2B ELISA Kit, 96T Antibodies Cooperates with TLR1 or TLR6Component of NMDA receptor complexes that function as heterotetrameric, ligand gated ion Channels with high calcium permeability and voltage dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate Channel inhibition by Mg(2+) (PubMed: 1350383, PubMed: 19910922, PubMed: 21677647, PubMed: 24876489,

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