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Treacle Polyclonal Antibody, 100ul Bottles MRE11A encodes a nuclear protein

SKU: 41668402851

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Treacle Polyclonal Antibody, 100ul Bottles MRE11A encodes a nuclear proteinTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

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Description

MRE11A encodes a nuclear protein involved in homologous recombination

FBN1 encodes a member of the fibrillin family of proteins

The enzyme encoded by this gene degrades type IV and V collagens

Is a receptor for leukotriene B4

Treacle Polyclonal Antibody, 100ul Bottles MRE11A encodes a nuclear proteinTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

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