Rat Integrin Alpha-1, ITGA1 ELISA Kit, 96T Measuring Instruments Light-induced isomerization of the chromophore

Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed: 8107847

GO annotations related to this gene include G-protein coupled receptor activity

Studies in other mammals suggest this protein plays a role in cell adhesion

It has been shown to interact with itself as well as with regulatory factors X2 and X3| but it does not interact with regulatory factor X1

Rat Integrin Alpha-1, ITGA1 ELISA Kit, 96T Measuring Instruments Light-induced isomerization of the chromophoreIntegrin alpha 1 beta 1 is a receptor for laminin and collagen. It recognizes the proline hydroxylated sequence G F P G E R in collagen. Involved in anchorage dependent, negative regulation of EGF stimulated cell growth (By similarity).