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TCF-4/12 Polyclonal Antibody, 50ul Hepatocytes Increased expression of this gene

SKU: 42913463242

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PLN162.00 PLN206.00

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TCF-4/12 Polyclonal Antibody, 50ul Hepatocytes Increased expression of this geneTCF4 encodes transcription factor 4, a basic helix loop helix transcription factor. The Transcription factor 4 recognizes an Ephrussi box ('E box') binding site ('CANNTG') a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10 37 repeat units

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Description

Increased expression of this gene is associated with colorectal cancer

The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes

phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway

this adapter is compatible with the VT1

TCF-4/12 Polyclonal Antibody, 50ul Hepatocytes Increased expression of this geneTCF4 encodes transcription factor 4, a basic helix loop helix transcription factor. The Transcription factor 4 recognizes an Ephrussi box ('E box') binding site ('CANNTG') a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10 37 repeat units

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