HoxA5 Polyclonal Antibody, 50ul Monoclonal Antibodies Mutations in this gene have

Mutations in this gene have been associated with familial dysautonomia

Mutations of this gene are associated with progressive pseudorheumatoid dysplasia

Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling

This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways

HoxA5 Polyclonal Antibody, 50ul Monoclonal Antibodies Mutations in this gene haveIn vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is part of the A cluster on chromosome 7 and encodes a DNA binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene