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EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligand

SKU: 43489348791

4.1
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EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligandKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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Description

in that its endogenous ligand has not been identified

The protein encoded by CDC5L (cell division cycle 5 like) shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product

and an intracellular C-terminus

consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC

EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligandKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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