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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage COL6A3 encodes the alpha-3 chain

SKU: 43664805198

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Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage COL6A3 encodes the alpha-3 chainThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

COL6A3 encodes the alpha-3 chain

Hirschsprung disease type 2

MDM4 encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus

Two transcript variants encoding different isoforms have been found for RAC1

Rb Polyclonal Antibody, 20ul[BT-AP07686] Liquid Handling &Storage COL6A3 encodes the alpha-3 chainThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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