PNKP Polyclonal Antibody, 50ul Site-directed Mutagenesis The inter-alpha-trypsin inhibitors (ITI) are

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis

The alpha subunit includes the skeletal muscle and hepatic isoforms| and the hepatic isoform is encoded by this gene

This gene has been identified as a tumor suppressor gene in several types of cancer

Belongs to the cyclophilin-type PPIase family

PNKP Polyclonal Antibody, 50ul Site-directed Mutagenesis The inter-alpha-trypsin inhibitors (ITI) areThis locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.