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K-Ras Polyclonal Antibody, 20ul Peptide Modification GATA2 (GATA binding protein 2)

SKU: 44656432057

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USD97.20 USD141.20

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K-Ras Polyclonal Antibody, 20ul Peptide Modification GATA2 (GATA binding protein 2)KRAS (KRAS proto oncogene, GTPase), a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing

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Description

GATA2 (GATA binding protein 2) encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes

One of the isoforms (CXCR3-B) shows high affinity binding to chemokine

Three transcript variants encoding the same protein have been found for this gene

POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumulation at resected ends (PubMed: 25642963)

K-Ras Polyclonal Antibody, 20ul Peptide Modification GATA2 (GATA binding protein 2)KRAS (KRAS proto oncogene, GTPase), a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing

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