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CCRL2 Polyclonal Antibody, 50ul Digital Burette Transcripts variants encoding different isoforms

SKU: 44732066819

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CCRL2 Polyclonal Antibody, 50ul Digital Burette Transcripts variants encoding different isoformsCCRL2 encodes a chemokine receptor like protein (C C motif chemokine receptor like 2), which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil

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Description

Transcripts variants encoding different isoforms have been described

It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide

It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein

their genes are pseudogenes

CCRL2 Polyclonal Antibody, 50ul Digital Burette Transcripts variants encoding different isoformsCCRL2 encodes a chemokine receptor like protein (C C motif chemokine receptor like 2), which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil

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