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AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis The ubiquitin associated domain is

SKU: 45141083953

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AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis The ubiquitin associated domain isAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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Description

The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle

Alternate splicing resultsi n multiple transcript variants

|PTM:Tyrosine phosphorylated (by SRC)

An important paralog of RAB29 is RAB7B

AQP2 Polyclonal Antibody, 100ul ssDNA Synthesis The ubiquitin associated domain isAquaporin 2 (AQP2) is a water transport protein that forms water channels in kidney tubules and plays a predominant role in controlling organism water homeostasis. Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus. This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due, in part, to either nonfunctional or mislocalized AQP2 protein.

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