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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization The protein encoded by this

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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization The protein encoded by thisDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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Description

The protein encoded by this gene is a member of the cyclin family of proteins

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif| two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors| one CHARLIE8 transposable element-like sequence| and a BED zinc finger

Like its somatic cell counterpart

Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization The protein encoded by thisDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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