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NIPA Polyclonal Antibody, 100ul Cryopreservation Defects in this gene have

SKU: 4614032086

4.4
PLN123.75 PLN160.75

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NIPA Polyclonal Antibody, 100ul Cryopreservation Defects in this gene haveZC3HC1 encodes an F box containing protein that is a component of an SCF type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2 M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

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Description

Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)

where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway

Does not demethylate histone H3 'Lys-4'

Pharmacokinetics/Pharmacodynamics and DNA Double-Strand Break Repair

NIPA Polyclonal Antibody, 100ul Cryopreservation Defects in this gene haveZC3HC1 encodes an F box containing protein that is a component of an SCF type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2 M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

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