FAM111B Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification This protein may also function

This protein may also function in the DNA damage response

Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers

The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors

It was shown that the activation occurs through phosphatidylinositol 3-kinase

FAM111B Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification This protein may also functionFAM111B encodes a protein with a trypsin like cysteine serine peptidase domain in the C terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog