DKK4 Polyclonal Antibody, 20ul Vector Construction in embryonic and tumor angiogenesis

in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor

CA XI is most abundantly expressed in brain

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation

DKK4 Polyclonal Antibody, 20ul Vector Construction in embryonic and tumor angiogenesisThis gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co receptor and the co factor kremen 2.