BEX3 Polyclonal Antibody, 20ul Protein Analysis VAV2 is the second member

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes

a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif

Expression of this gene is activated by the phosphatase and tensin homolog

This gene encodes a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein

BEX3 Polyclonal Antibody, 20ul Protein Analysis VAV2 is the second memberThe nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR NGFR.,May be a signaling adapter molecule involved in p75NTR mediated apoptosis induced by NGF. Plays a role in zinc triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous: Binds transition metals.,PTM: Ubiquitinated. Degraded by the proteasome.,Belongs to the BEX