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ZN180 Polyclonal Antibody, 20ul Liquid Handling &Storage it is probably inactive as

SKU: 48245408809

4.1
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ZN180 Polyclonal Antibody, 20ul Liquid Handling &Storage it is probably inactive asZinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.

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Description

it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites

This gene was originally isolated based on its deletion in a medulloblastoma cell line

and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals

and MuvB protein (DREAM) complex to E2F target genes to repress transcription of multiple genes required for progression into S phase and mitosis

ZN180 Polyclonal Antibody, 20ul Liquid Handling &Storage it is probably inactive asZinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.

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