Sgo1 Polyclonal Antibody, 20ul Peptide Modification suggesting a role as the

suggesting a role as the regulatory subunit

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and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4)

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Sgo1 Polyclonal Antibody, 20ul Peptide Modification suggesting a role as theShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found