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PCAF Polyclonal Antibody, 100ul[BT-AP06968] Petri Dishes Numerous alternatively spliced transcript variants

SKU: 48540568180

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PCAF Polyclonal Antibody, 100ul[BT-AP06968] Petri Dishes Numerous alternatively spliced transcript variantsCBP and p300 are large nuclear proteins that bind to many sequence specific factors involved in cell growth and or differentiation, including c jun and the adenoviral oncoprotein E1A. Lysine acetyltransferase 2B encoded by KAT2B associates with p300 CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300 CBP. It has histone acetyl transferase activity with core histones and nucleosome core

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Description

Numerous alternatively spliced transcript variants encoding different isoforms have been described

PTM:Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease

This kinase undergoes autophosphorylation

This gene is thought to play a role in the regulation of myofibrillogenesis

PCAF Polyclonal Antibody, 100ul[BT-AP06968] Petri Dishes Numerous alternatively spliced transcript variantsCBP and p300 are large nuclear proteins that bind to many sequence specific factors involved in cell growth and or differentiation, including c jun and the adenoviral oncoprotein E1A. Lysine acetyltransferase 2B encoded by KAT2B associates with p300 CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300 CBP. It has histone acetyl transferase activity with core histones and nucleosome core

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