NTCP2 Rabbit Polyclonal Antibody, 100ul CellSafe™ A pseudogene on chromosome 1p31

A pseudogene on chromosome 1p31 exists for this gene

Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus

coincident with the appearance of thyroid-stimulating hormone

Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response

NTCP2 Rabbit Polyclonal Antibody, 100ul CellSafe™ A pseudogene on chromosome 1p31This gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines