Phospho-Akt (Y326) Polyclonal Antibody, 50ul Pipette Filler The PDZ-binding motif is essential

The PDZ-binding motif is essential for stimulated gene transcription

The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype

Wolman’s syndrome

The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection

Phospho-Akt (Y326) Polyclonal Antibody, 50ul Pipette Filler The PDZ-binding motif is essentialThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a