Integrin beta 2(Phospho Thr758) Polyclonal Antibody, 100ul Microbial Genome Editing E3 ubiquitin protein ligase is

E3 ubiquitin protein ligase is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif

The F-box proteins are divided into three classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs

Defects in this gene are a cause of Bernard-Soulier syndrome

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct

Integrin beta 2(Phospho Thr758) Polyclonal Antibody, 100ul Microbial Genome Editing E3 ubiquitin protein ligase isThis gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.