Rho A Polyclonal Antibody, 50ul Polyclonal Antibody Preparation Defects in this gene are

Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB)

Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354

possibly by inhibition of mRNA stabilization

Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion

Rho A Polyclonal Antibody, 50ul Polyclonal Antibody Preparation Defects in this gene areRHOA encodes a member of the Rho family of small GTPases, which cycle between inactive GDP bound and active GTP bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.