ALS2 Polyclonal Antibody, 20ul Serum & Sample Tubes Proteins of this subgroup are

Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands

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This gene encodes a protein that is secreted by white adipocytes

Mutations in PHKA1 cause glycogen storage disease type 9D

ALS2 Polyclonal Antibody, 20ul Serum & Sample Tubes Proteins of this subgroup areThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.