IRS-1 Polyclonal Antibody, 100ul[BT-AP04642] DNA Oligo Synthesis The type I isozyme has

The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities

a process required for the histone to proamine transition in spermatogenesis

Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains

It is now widely accepted that KSR1 functions as a scaffold that binds MEK1/2 and 14-3-3 protein constitutively and binds ERK1/2 in a Ras activation-dependent manner

IRS-1 Polyclonal Antibody, 100ul[BT-AP04642] DNA Oligo Synthesis The type I isozyme hasIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.