CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries Additional splicing is suggested but

Additional splicing is suggested but complete sequence for further transcripts has not been determined

Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing

Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis

and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53)

CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries Additional splicing is suggested butCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin