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BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have been

SKU: 51752571041

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BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have beenBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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Description

Mutations in PAX8 have been associated with thyroid dysgenesis

which is also true for SGK

Probably involved in a neuron-specific signal transduction

It associates with protein kinases A and C and phosphatase

BLMH Rabbit Polyclonal Antibody, 20ul Miscellaneous Mutations in PAX8 have beenBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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