MEK3 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

RAD17 checkpoint clamp loader component shares strong similarity with DNA replication factor C (RFC)

The encoded peptides have been shown to regulate gastric acid secretion and food intake

Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP)

MEK3 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification Several alternatively spliced transcript variantsThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase mediated signaling cascade. It phosphorylates and thus activates MAPK14 p38 MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the