p27(Phospho Thr187) Polyclonal Antibody, 50ul Cell Culture & Maintenance stem cells and other fastidious

stem cells and other fastidious cells that have more stringent requirements for the hydrophilicity of the culture surface

This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers

This protein mediates the signal transduction triggered by various cell ligands

May be involved in the transcriptional activation of MDM2 and EP300 genes

p27(Phospho Thr187) Polyclonal Antibody, 50ul Cell Culture & Maintenance stem cells and other fastidiousThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from