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FBW1A Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers MPP6 is a member of

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FBW1A Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers MPP6 is a member ofThis gene encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either

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Description

MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al

The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+)

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

FBW1A Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers MPP6 is a member ofThis gene encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either

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