Cytokeratin 18 Monoclonal Antibody(1B3), 50ul PCR Series Binding of insulin to the

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake

it translocates to the plasma membrane

The encoded preproprotein is proteolytically processed by furin to generate the mature receptor

This gene encodes a subunit of the ORC complex

Cytokeratin 18 Monoclonal Antibody(1B3), 50ul PCR Series Binding of insulin to theKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.