CaSR Polyclonal Antibody, 50ul[BT-AP14680] Gene Synthesis The domain structure of alpha

The domain structure of alpha 4 is similar to that of alpha 3

Contains 1 Ig-like C1-type (immunoglobulin-like) domain

Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR)

together with LMNA

CaSR Polyclonal Antibody, 50ul[BT-AP14680] Gene Synthesis The domain structure of alphaThe protein encoded by this gene is a G protein coupled receptor that is expressed in the parathyroid hormone (PTH) producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion