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PKI Beta Polyclonal Antibody, 50ul Site-directed Mutagenesis RRN3 (RRN3 Homolog

SKU: 54377218910

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DKK142.00 DKK192.00

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PKI Beta Polyclonal Antibody, 50ul Site-directed Mutagenesis RRN3 (RRN3 HomologPKIB (protein kinase (cAMP dependent, catalytic) inhibitor beta) encodes a member of the cAMP dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of PKIB may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PKIB.

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Description

RRN3 (RRN3 Homolog

Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis

Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death

It has been associated with multiple functions

PKI Beta Polyclonal Antibody, 50ul Site-directed Mutagenesis RRN3 (RRN3 HomologPKIB (protein kinase (cAMP dependent, catalytic) inhibitor beta) encodes a member of the cAMP dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of PKIB may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PKIB.

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