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It may also be required for the assembly of membrane and secretory proteins

and in mouse it has been shown to be required for double-stranded RNA induction of these genes

Multiple transcript variants encoding different isoforms have been found for FLT1

BNI3L Polyclonal Antibody, 20ul Culture Media Take the risk out ofThis gene encodes a protein that belongs to the pro apoptotic subfamily within the Bcl 2 family of proteins. The encoded protein binds to Bcl 2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c.