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FA9 Rabbit Polyclonal Antibody, 50ul[BT-AP02612] Peptide Modification Contains 1 N-terminal Ras-GEF domain

SKU: 55166610483

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FA9 Rabbit Polyclonal Antibody, 50ul[BT-AP02612] Peptide Modification Contains 1 N-terminal Ras-GEF domainThis gene encodes vitamin K dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions

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Description

Contains 1 N-terminal Ras-GEF domain

RAD17 checkpoint clamp loader component shares strong similarity with DNA replication factor C (RFC)

In B-cells

Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA)

FA9 Rabbit Polyclonal Antibody, 50ul[BT-AP02612] Peptide Modification Contains 1 N-terminal Ras-GEF domainThis gene encodes vitamin K dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions

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