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INPP5J Polyclonal Antibody, 100ul Protein Analysis The small GTPase RAN (MIM

SKU: 55541202683

4.2
SEK123.75 SEK172.75

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INPP5J Polyclonal Antibody, 100ul Protein Analysis The small GTPase RAN (MIMInositol 5 phosphatase, which converts inositol 1,4,5 trisphosphate to inositol 1,4 bisphosphate. Also converts phosphatidylinositol 4,5 bisphosphate to phosphatidylinositol 4 phosphate and inositol 1,3,4,5 tetrakisphosphate to inositol 1,3,4 trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate binding proteins that are present at membranes ruffles.

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Description

The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import

The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility

The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes

|PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes

INPP5J Polyclonal Antibody, 100ul Protein Analysis The small GTPase RAN (MIMInositol 5 phosphatase, which converts inositol 1,4,5 trisphosphate to inositol 1,4 bisphosphate. Also converts phosphatidylinositol 4,5 bisphosphate to phosphatidylinositol 4 phosphate and inositol 1,3,4,5 tetrakisphosphate to inositol 1,3,4 trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate binding proteins that are present at membranes ruffles.

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