PSMD9 Polyclonal Antibody, 20ul Cell fragmentation and collection Mice lacking this gene are

Mice lacking this gene are also hypersensitive to interferon| suggesting a function of this protein in downregulating interferon responses| independent of its isopeptidase activity towards ISG15

a disease characterized by acute renal failure

Two of the protein's effects

subcellular location:Expressed diffusely throughout the nucleus

PSMD9 Polyclonal Antibody, 20ul Cell fragmentation and collection Mice lacking this gene areThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non ATPase subunits, and a lid, which contains up to 10 non ATPase subunits.