Mouse Fetuin-B, Fetub ELISA Kit, 5*96T Stepper activates by depolarization POMC neurons

activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic Peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic Peptides (By similarity) (PubMed: 20620997

Binds LRP1

Loss of function or expression of this gene is associated with decreased apoptosis

It functions as an oxidoreductase| and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways| promote mitochondrial biogenesis and mitochondrial function| and suppress cellular senescence through genome maintenance and redox regulation

Mouse Fetuin-B, Fetub ELISA Kit, 5*96T Stepper activates by depolarization POMC neurons