POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies SIX2 is a member of

SIX2 is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins

Mutation analysis of this gene has not revealed any mutation which causes the CPX disorder

Primary dendritic cells (DCs) also to express HLA-DO

POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies SIX2 is a member ofThe exact function of the protein encoded by this gene is not known. However this gene product contains a KRAB domain (which is involved in protein protein interactions) at the N terminus and a transposase domain at the C terminus suggesting that it may belong to the family of DNA mediated transposons in human.