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Raf-1(Phospho Ser43) Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Study of its expression in

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Raf-1(Phospho Ser43) Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Study of its expression inThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid

This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene

activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed

This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens

Raf-1(Phospho Ser43) Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Study of its expression inThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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