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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 100ul RNA Synthesis and transport 5-methyltetrahydrofolate into cells

SKU: 57491274576

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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 100ul RNA Synthesis and transport 5-methyltetrahydrofolate into cellsThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

and transport 5-methyltetrahydrofolate into cells

A pseudogene of ACKR4 is found on chromosome 6

The protein is phosphorylated by several protein kinases

Fibroblast cells from CAID patients exhibited both increased cell proliferation and higher rates of senescence

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 100ul RNA Synthesis and transport 5-methyltetrahydrofolate into cellsThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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