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CCDB1 Rabbit Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene are

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CCDB1 Rabbit Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areThis gene was identified by the interaction of its gene product with Grap2, a leukocyte specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D dependent protein kinase, and inhibit E2F1 mediated transcription activity. This protein was also found to interact with helix

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Description

Mutations in this gene are associated with type II vitamin D-resistant rickets

The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin

the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end

which may be important for the inhibition of keratinocyte proliferation

CCDB1 Rabbit Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areThis gene was identified by the interaction of its gene product with Grap2, a leukocyte specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D dependent protein kinase, and inhibit E2F1 mediated transcription activity. This protein was also found to interact with helix

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