ErbB-3 Polyclonal Antibody, 100ul[BT-AP03039] Antibody Humanization which is involved in axon

which is involved in axon elongation

Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies

The mouse ortholog also functions in the determination of left-right asymmetry

Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03039] Antibody Humanization which is involved in axonERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation