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Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may be

SKU: 57938630601

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Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may beThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence

eotaxin-3 (CCL26)

as well as in modulating the secondary immune response by co-stimulating memory T-cell function

Phospho-Akt (S124) Polyclonal Antibody, 50ul Custom RNA Oligos The encoded protein may beThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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