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ASC-1 Polyclonal Antibody, 100ul Centrifuges The active| hypophosphorylated form of

SKU: 57971595888

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ASC-1 Polyclonal Antibody, 100ul Centrifuges The active| hypophosphorylated form ofTRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC 1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors mediated transcription. This protein is localized in the nucleus and contains an E1A type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand

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Description

The active| hypophosphorylated form of the protein binds transcription factor E2F1

The encoded protein has been shown to undergo autophosphorylation

More variants exist| but their full-length natures have yet to be determined

This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

ASC-1 Polyclonal Antibody, 100ul Centrifuges The active| hypophosphorylated form ofTRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC 1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors mediated transcription. This protein is localized in the nucleus and contains an E1A type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand

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