APEX2 Rabbit Polyclonal Antibody, 100ul Molecular Biology The encoded protein binds to

The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis

and 36 kDa

The gene is specific to the primate lineage

chromosome 10 makes up approximately 4

APEX2 Rabbit Polyclonal Antibody, 100ul Molecular Biology The encoded protein binds toApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II