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AR Polyclonal Antibody, 50ul[BT-AP14284] Peptide Library It is a transcriptional repressor

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AR Polyclonal Antibody, 50ul[BT-AP14284] Peptide Library It is a transcriptional repressorThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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Description

It is a transcriptional repressor of genes that require a bHLH protein for their transcription

This gene is down-regulated in intestinal type gastric cancer

Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons

3 potential N-myristoylation sites

AR Polyclonal Antibody, 50ul[BT-AP14284] Peptide Library It is a transcriptional repressorThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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