Rat Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit , 96T Cell Culture Flasks Knockout studies in mice suggest

Knockout studies in mice suggest that this gene plays a role in T-helper cell activation

Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence

Acts also inhibitory in T-cells (By similarity)

Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed: 25355627

Rat Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit , 96T Cell Culture Flasks Knockout studies in mice suggestOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.